PIRE was leading cross-sectional survey data collection in order to collect prevalence data on key substance use behaviors among youth, including use of alcohol, tobacco, e-cigs, marijuana, and prescription drugs. The sample comprised of 3,000 youth in rural Tennessee in grades 6, 8, 10, and 12. Analyses looked at prevalence of substance use behaviors and correlates and predictors of use, including demographics, individual characteristics, rurality, exposure to marketing, exposure to prevention messaging, and attitudes and norms about substance use. Data was used, in part, to support needs assessments and community and state-wide planning.